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The Buffalo Bills battle the Los Angeles Rams in the first game of the 2022 NFL season. Ahead of the highly-anticipated matchup, the Bills have ruled out five players:
Doyle (foot) and Morris (hamstring) carried injury designations throughout the week and will not play against the Rams. Doyle and Morris were held out of Monday and Tuesday’s practices but logged a full participation on Wednesday before being ruled out for Thursday’s game.
Shakir was the Bills’ fifth-round draft pick this year but will have to wait to make his NFL debut.
The Bills and Rams kickoff at 8:20 p.m. on NBC.
The Bills have arrived at SoFi Stadium to start the 2022 regular season. This gallery is presented by Imagine Staffing.
Stefon Diggs (14). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Gabe Davis (13). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Gabe Davis (13). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Rodger Saffold (76) Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Spencer Brown (79). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Matt Barkley (11). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Dawson Knox (88). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Case Keenum (18). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Spencer Brown (79). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Jaquan Johnson (4). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Jaquan Johnson (4) Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Mitch Morse (60). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Von Miller (40). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Von Miller (40). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Von Miller (40). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Von Miller (40). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Tim Settle (99). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Tim Settle (99). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Zack Moss (20). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Micah Hyde (23). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Dion Dawkins (73). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Reggie Gilliam (41). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Jordan Phillips (97). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Devin Singletary (26). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Matt Milano (58). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Boogie Basham (55). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Taron Johnson (7). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Greg Rousseau (50). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Tremaine Edmunds (49). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Jordan Poyer (21). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Tommy Sweeney (89). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Kaiir Elam (24), Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Boogie Basham (55). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Zack Moss (20). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium.
Defensive tackle Vernon Butler is the most notable inactive designation for today’s game.
Efe Obada, Marquez Stevenson among the Bills who will not play on Saturday night.
Bills placed two wide receivers on the inactive list.
The Bills will be without a starting wide receiver against the Falcons.
Dion Dawkins, Zack Moss are some of the notable players who will be active this week.
Star Lotulelei returns to the lineup after missing last week’s game.
Wide receivers Isaiah McKenzie and Marquez Stevenson are active.
Two wide receivers are inactive for the Bills.
Marquez Stevenson is set to make his NFL debut.
The middle linebacker will miss his second consecutive game.
The Bills will have four active running backs on Sunday against the Jets.
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